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Visor de contenido de Grupo - TECNOLOGÍAS DE MODELADO, PROCESAMIENTO Y GESTIÓN DEL CONOCIMIENTO

El Máster Universitario en Bioinformática organiza dos conferencias que se celebrarán el martes 19 y el jueves 21 de abril

El Máster Universitario en Bioinformática organiza dos conferencias que se celebrarán el martes 19 y el jueves 21 de abril

HORARIO: martes 19 de abril de 2016, a las 12:00

LUGAR: Salón de Grados de la Facultad de Biología, Universidad de Murcia

TÍTULO: "Ontologies of phenotypes and their applications in personalized medicine"

RESUMEN:The development of formal ontologies for the description of phenotypes for many species including mice and humans has revolutionized our ability to analyse the effects of mutations, elucidate the molecular basis of disease, develop animal models and analyse high throughput experiments. In my talk I will discuss our research on the creation and application of phenotype ontologies to human genomic medicine with an emphasis on the use of phenotypes for disease gene prioritization and understanding the relationships between phenotype and genotype. I will demonstrate how formal ontological analysis and reasoning using the Web Ontology Language (OWL) can not only improve our ability to integrate data but also help to understand the pathobiology of human disease. Finally, I will demonstrate ontology-based tools for analyzing clinical phenotype and genotype data and their application to identifying causal variants for rare disease from personal genomes.

PONENTE: Dr. Robert Hoehndorf (Computational Bioscience Research Center, King Abdullah University of Science and Technology)

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HORARIO: jueves 21 de abril de 2016, a las 12:00

LUGAR: Sala de Grados, Facultad de Biología, Universidad de Murcia

TÍTULO: "Computational Modeling of Biochemical Networks with COPASI"

RESUMEN: Modeling and computer simulation are becoming standard approaches to understand complex biochemical processes. Modeling consists of identifying the essential features of a system and translating them mathematically through several parameters and functions. Simulation consists of solving the equations at different values of the parameters essentially to answer questions that ask how the parameters affect the system. I will present COPASI, a user-friendly biochemical modeling and simulation software that offers several unique features. COPASI helps the user to define models without much mathematical background, yet it provides several advanced simulation tasks. This includes solution and characterization of steady states, time course simulations with deterministic and stochastic approaches, parameter estimation, optimization and sensitivity analysis. This open source software is available from http://www.copasi.org

PONENTE: Dr. Pedro Mendes, Professor of Computational Systems Biology ( School of Computer Science and Manchester Institute of Biotechnology,  University of Manchester), Professor (Center for Quantitative Biology, University of Connecticut Health Center)

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Ambas charlas serán en inglés y la duración estimada de cada una es de 90 minutos.

Instituto de Investigación Sanitaria Acreditado

ISCII

TECNOLOGÍAS DE MODELADO, PROCESAMIENTO Y GESTIÓN DEL CONOCIMIENTO